The goal of anti-inflammatory diets is to reduce chronic low-grade inflammation, the leading cause of most health problems such as cardiovascular disease, diabetes, arthritis, and anthologies of some cancers. Anti-inflammatory diets promote foods that are packed with nutrients, such as fruits, vegetables, whole grains, fatty fish, legumes, nuts, and seeds while reducing processed foods, refined carbohydrates, and trans fats. The Mediterranean diet is one of the most recognized examples of an anti-inflammatory diet, as it emphasizes antioxidants, omega-3 fatty acids, and phytonutrients for immune health and anti-inflammatory effect. This session will describe the science of anti-inflammatory nutrition, food choice based in the real world, and practical strategies that can be used in patient care and in day-to-day life that can promote long-term health.