Weight loss and lifestyle interventions are key strategies in the prevention and management of obesity and long-term health. Unlike restrictive dieting, these methods prioritize overall nutrition, regular exercise, and sustainable behaviors integrated into daily living. Evidence-based programs combine dietary change, exercise prescription, stress reduction, and sleep hygiene in support of gradual and sustained weight loss and prevention of chronic diseases. This session will examine real-world life-style strategies, patient-focussed interventions, and new research that demonstrate how a synthesis of nutrition, physical activity, and behavioral support can result in weight management success that is sustained.